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World's Most Powerful Antioxidant Bestseller for Over 30 Years Only Isotonic Pycnogenol® in the World 18 Million Sold Worldwide

by: Isotonix®

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  • Feel Young and Stay Healthy with Isotonix OPC-3®

    Results matter. With the unmatched 95% nutrient delivery of Isotonix OPC-3®, feel the life-changing difference in your energy, muscles and joint performance. 

    Powered by Pycnogenol®—nature’s most powerful antioxidant—this formula aids oxygen delivery, fuels vital organs and combats signs of aging. Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed for your health and longevity!

  • Active Ingredients: Grape seed extract, pine bark extract (Pycnogenol®), red wine extract, bilberry extract, citrus bioflavonoid complex

    Other ingredients: Fructose, glucose, citric acid, potassium bicarbonate, maltodextrin, silica, calcium sulfate, food starch (modified), apple pectin, stearic acid.   

Formulated as the best antioxidant

Validated by research

20x

stronger than vitamin C

50x

stronger than vitamin E

95%

intestinal nutrient delivery for max absorption

Oligomeric proanthocyanadins (OPCs) are bioflavonoids (complex organic compounds) found in fruits, vegetables and certain tree barks that provide exceptional nutritional benefits to the human body.

image of pinetree bark

The Super Antioxidant in OPC-3, Pycnogenol®‡

Isotonix OPC-3 contains the only isotonic form of Pycnogenol® in the world. Pycnogenol® is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and potent bioflavonoid.

Product Classifications

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Gluten-Free

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No Detectable GMO

image of glass containing liquid

Isotonic

image of Vegan

Vegan

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Good Manufacturing Practices

image of a bottle of milk with a line through it

Dairy Free

Directions for Use

Image of person pouring one level cap of Isotonix powder into cup

Pour 1 small capful (3.3 g) of powder into a cup.

Image of mixed Isotonix OPC-3 with water in cup.

Add water 2 fl. oz/60 mL of water for each capful and stir.

image of a woman holding a cup with mixed Isotonix OPC-3

Enjoy once a day. For maximum absorption take on an empty stomach.

Key Ingredients & Their Benefits

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Grape Seed Extract*

Maintains healthy cholesterol levels

image of red wine in a wooden spoon
Red Wine Extract*

Powerful antioxidant

image of blueberries against a purple background
Bilberry Extract*

Powerful antioxidant

Supports healthy vision

Maintains healthy circulation

image of citrus fruits against a purple background
Citrus Extract (Bioflavaniods)*

Promotes cardiovascular health

Maintains healthy circulation

image of pine bark
Pycnogenol®‡, Pine Bark Extract*

Supports the normal dilation of blood vessels

Provides complete antioxidant protection

Combats free radicals

Supports a healthy complexion

Promotes healthy sperm quality

World's Most Powerful Antioxidant

Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed to supercharge health and longevity!

:05 minutes

Isotonix Liquid Vitamins

  • Formulated to survive digestion.
  • Delivers concentrated nutrients to the site of absorption.
  • Contains no fillers or binders.
  • No artificial color or flavors. 


:40 minutes

Standard Vitamin Tablet

  • Contains lab-created coatings and lubricants.
  • Often contains artificial colors, nutrients and flavors.
  • Limited absorption of nutrient utilization. 

Frequently Asked Questions

  • Isotonix OPC-3 contains bioflavonoids, plant compounds that support cardiovascular health, healthy circulation and skin, joint and tissue integrity; it uses a unique Isotonix delivery system for fast, effective absorption and includes scientifically proven antioxidants to fight free radicals, making it one of the most powerful products available.

  • Thanks to its liquid, isotonic form, Isotonix OPC-3 is absorbed quickly by the small intestine, entering the bloodstream within minutes; this rapid absorption allows the body to benefit almost immediately.

  • Free radicals cause oxidative stress, which contributes to aging, circulation and heart and immune health. OPCs are powerful antioxidants — with more staying power than vitamins C and E — that help neutralize free radicals. Taking OPC-3 daily is essential for combating free radical damage and promoting health.

  • Even athletes experience free radical damage from increased oxygen use during exercise, which can affect muscle performance and endurance. Studies show OPCs promote endurance, reduce mild muscle cramps and support healthy blood flow, helping muscles recover and perform.

  • Yes, studies show OPCs can help mensural cramps.

  • Pycnogenol® is a patented extract from French maritime pine bark, supported by over 120 clinical studies; it acts as a powerful antioxidant, helping maintain healthy circulation, blood pressure and blood vessel function by promoting nitric oxide production.

Research Scope on OPC-3

view full Reference List

558+

Studies on Pycnogenol® and Human Health

100

The number of active compounds found in Red Wine Extract

3

Independent studies for Isotonix OPC-3®

4x

The bioavailability of Isotonix OPC-3® compared to a tablet form

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

Reviews


Customer Reviews
  • (308)
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  • (4)
  • (19)
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Displaying reviews 1 - 5 of 373

by BridgetB

  • Shop Consultant
5year old never skips a day of her OPC!

She likes to mix it herself every single day!!

Response from Customer Service:

Thank you so much for your review of Isotonix OPC-3® for Adults & Children Ages 4+! We're delighted to hear your 5-year-old enjoys mixing it herself every day. Your feedback is wonderful, and we appreciate you sharing your family's routine. Thank you for being valued customers!

by RoxanneR

  • Shop Consultant
I love OPC-3

I love OPC-3 because of it's Rapid Delivery to the Small Intestine
The small intestine is where most nutrient absorption occurs.
Because the solution is already isotonic, nutrients can pass quickly from the stomach into the small intestine, where they are absorbed.
I have been taking OPC-3 daily for 26 years! Optimal Health at the age of 73!

Response from Customer Service:

Thank you so much for your fantastic review of Isotonix OPC-3® for Adults & Children Ages 4+! We're thrilled to hear you've been enjoying the benefits of rapid nutrient delivery for 26 years. Your dedication and enthusiasm are truly inspiring, and we appreciate your continued trust in Isotonix OPC-3®. Thank you for being a valued customer!

by JulieL

  • Shop Consultant
My #1 Supplement

OPC-3 has been my #1 supplement since introduced in 2010! And my body loves the Isotonix formulation! What a game changer for me & my patients!

Response from Customer Service:

Thank you so much for your fantastic review of nutraMetrix Isotonix OPC-3® for Adults & Children Ages 4+! We're thrilled to hear it's been your top supplement since 2010 and that you and your patients appreciate the Isotonix formulation. Your feedback and support mean a great deal to us. Thank you for being a valued customer!

by GinnyH

  • Shop Consultant
Most comprehensive anti-oxidant

Nothing beats OPC-3. It should be the4 baseline antioxidant in any formula but this product is the only truly isotonic-capable one that I've seen on the market.

Response from Customer Service:

Thank you so much for your thoughtful review! We couldn’t agree more, the Isotonix OPC-3® is truly one of a kind. We're proud to offer a product with such powerful antioxidants in an isotonic-capable formula, and it’s wonderful to hear that you value its quality and effectiveness. Thank you for your support and for choosing Isotonix OPC-3 as your go-to antioxidant supplement!

by LUANNN

Absolutely Fantastic

Love OPC been taking it for over 25 years.. Of all the supplements I've taken and tried through the years OPC has been the best and I will continue to take it everyday.

Response from Customer Service:

Thank you for your wonderful review! It’s awesome to know that you have been part of the Isotonix family for over 25 years and still hold the same love and appreciation for Isotonix OPC-3® for Adults & Children Ages 4+ since the beginning. Your continued loyalty and positive experience truly mean a lot to us. Thank you for making Isotonix OPC-3® a trusted part of your daily routine and for being such a valued customer!