Isotonix OPC-3® for Adults & Children Ages 4+

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World's Most Powerful Antioxidant Bestseller for Over 30 Years Only Isotonic Pycnogenol® in the World 18 Million Sold Worldwide

by: Isotonix®

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  • Feel Young and Stay Healthy with Isotonix OPC-3®

    Results matter. With the unmatched 95% nutrient delivery of Isotonix OPC-3®, feel the life-changing difference in your energy, muscles and joint performance. 

    Powered by Pycnogenol®—nature’s most powerful antioxidant—this formula aids oxygen delivery, fuels vital organs and combats signs of aging. Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed for your health and longevity!

  • Active Ingredients: Grape seed extract, pine bark extract (Pycnogenol®), red wine extract, bilberry extract, citrus bioflavonoid complex

    Other ingredients: Fructose, glucose, citric acid, potassium bicarbonate, maltodextrin, silica, calcium sulfate, food starch (modified), apple pectin, stearic acid.   

Formulated as the best antioxidant

Validated by research

20x

stronger than vitamin C

50x

stronger than vitamin E

95%

intestinal nutrient delivery for max absorption

Oligomeric proanthocyanadins (OPCs) are bioflavonoids (complex organic compounds) found in fruits, vegetables and certain tree barks that provide exceptional nutritional benefits to the human body.

image of pinetree bark

The Super Antioxidant in OPC-3, Pycnogenol®‡

Isotonix OPC-3 contains the only isotonic form of Pycnogenol® in the world. Pycnogenol® is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and potent bioflavonoid.

Product Classifications

Image of wheat with a line through it

Gluten-Free

image of lab beaker

No Detectable GMO

image of glass containing liquid

Isotonic

image of Vegan

Vegan

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Good Manufacturing Practices

image of a bottle of milk with a line through it

Dairy Free

Directions for Use

Image of person pouring one level cap of Isotonix powder into cup

Pour 1 small capful (3.3 g) of powder into a cup.

Image of mixed Isotonix OPC-3 with water in cup.

Add water 2 fl. oz/60 mL of water for each capful and stir.

image of a woman holding a cup with mixed Isotonix OPC-3

Enjoy once a day. For maximum absorption take on an empty stomach.

Key Ingredients & Their Benefits

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Grape Seed Extract*

Maintains healthy cholesterol levels

image of red wine in a wooden spoon
Red Wine Extract*

Powerful antioxidant

image of blueberries against a purple background
Bilberry Extract*

Powerful antioxidant

Supports healthy vision

Maintains healthy circulation

image of citrus fruits against a purple background
Citrus Extract (Bioflavaniods)*

Promotes cardiovascular health

Maintains healthy circulation

image of pine bark
Pycnogenol®‡, Pine Bark Extract*

Supports the normal dilation of blood vessels

Provides complete antioxidant protection

Combats free radicals

Supports a healthy complexion

Promotes healthy sperm quality

World's Most Powerful Antioxidant

Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed to supercharge health and longevity!

:05 minutes

Isotonix Liquid Vitamins

  • Formulated to survive digestion.
  • Delivers concentrated nutrients to the site of absorption.
  • Contains no fillers or binders.
  • No artificial color or flavors. 

:40 minutes

Standard Vitamin Tablet

  • Contains lab-created coatings and lubricants.
  • Often contains artificial colors, nutrients and flavors.
  • Limited absorption of nutrient utilization. 

Frequently Asked Questions

  • Isotonix OPC-3 contains bioflavonoids, plant compounds that support cardiovascular health, healthy circulation and skin, joint and tissue integrity; it uses a unique Isotonix delivery system for fast, effective absorption and includes scientifically proven antioxidants to fight free radicals, making it one of the most powerful products available.

  • Thanks to its liquid, isotonic form, Isotonix OPC-3 is absorbed quickly by the small intestine, entering the bloodstream within minutes; this rapid absorption allows the body to benefit almost immediately.

  • Free radicals cause oxidative stress, which contributes to aging, circulation and heart and immune health. OPCs are powerful antioxidants — with more staying power than vitamins C and E — that help neutralize free radicals. Taking OPC-3 daily is essential for combating free radical damage and promoting health.

  • Even athletes experience free radical damage from increased oxygen use during exercise, which can affect muscle performance and endurance. Studies show OPCs promote endurance, reduce mild muscle cramps and support healthy blood flow, helping muscles recover and perform.

  • Yes, studies show OPCs can help mensural cramps.

  • Pycnogenol® is a patented extract from French maritime pine bark, supported by over 120 clinical studies; it acts as a powerful antioxidant, helping maintain healthy circulation, blood pressure and blood vessel function by promoting nitric oxide production.

Research Scope on OPC-3

view full Reference List

558+

Studies on Pycnogenol® and Human Health

100

The number of active compounds found in Red Wine Extract

3

Independent studies for Isotonix OPC-3®

4x

The bioavailability of Isotonix OPC-3® compared to a tablet form

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

‡As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

Reviews

Customer Reviews
  • (305)
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Displaying reviews 1 - 5 of 370

by GinnyH

  • Shop Consultant
Most comprehensive anti-oxidant

Nothing beats OPC-3. It should be the4 baseline antioxidant in any formula but this product is the only truly isotonic-capable one that I've seen on the market.

by LUANNN

Absolutely Fantastic

Love OPC been taking it for over 25 years.. Of all the supplements I've taken and tried through the years OPC has been the best and I will continue to take it everyday.

Response from Customer Service:

Thank you for your wonderful review! It’s awesome to know that you have been part of the Isotonix family for over 25 years and still hold the same love and appreciation for Isotonix OPC-3® for Adults & Children Ages 4+ since the beginning. Your continued loyalty and positive experience truly mean a lot to us. Thank you for making Isotonix OPC-3® a trusted part of your daily routine and for being such a valued customer!

by BonnieP

  • Shop Consultant
OPC3 is an all time lifer product

For over 28 years OPC3 has been our non negotiable supplement. It is the world's most powerful antioxident and has assisted in blessing me with good health.
Thank you Market America!

Response from Customer Service:

Thank you so much for your wonderful review! It’s inspiring to hear that you’ve made Isotonix OPC-3® for Adults & Children Ages 4+ a non-negotiable part of your routine for over 28 years. Your ongoing loyalty and appreciation mean a great deal to us. Thank you for your kind words and for being a valued part of the Isotonix family, your support truly motivates us every day!

by MichaelT

OPC-3

Been using this product for over a decade and I know it has been very beneficial to my overall health, top notch quality and service on all the products from Shop. com, thanks again...

Response from Customer Service:

Thank you so much for your loyal support and wonderful feedback on Isotonix OPC-3®! We’re delighted to hear you’ve been enjoying the product for over a decade and that you’ve had a great experience with our quality and service. Your trust and satisfaction mean a great deal to us. Thank you for choosing Shop.com and Isotonix® as part of your wellness journey!

by suniw

  • Shop Consultant
25 years and growing!

I have taken this product for 25 years plus and I would rather leave my cell phone at home than to go without this product. Thank me later!

Response from Customer Service:

Thank you so much for sharing your incredible dedication to Isotonix OPC-3® over the past 25 years! We're honored that you consider it an essential part of your daily routine and appreciate your passion for the product. Your loyalty and enthusiasm mean a lot to us. Thank you for being such a valued member of our community!

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