Boost your B vitamins with our active forms of vitamins B6 &B12 & folic acid
- Increases energy & fuels optimal energy production
- Promotes a healthy nervous system, bone marrow & intestinal tract
- Promotes cardiovascular health
- Maintains healthy levels of serotonin, thereby decreasing stress & improving mood
Additional Benefits -
- Meets need for B vitamins in a vegetarian diet
- Promotes healthy levels of homocysteine
- Promotes normal cognitive performance
- Contains activated forms of select B vitamins to ensure optimal utilization by the body
- No Detectable GMOs
- Isotonic-Capable Drinkable Supplements
Why Choose Isotonix B-Complex?
Isotonix Activated B-Complex delivers metabolically active forms of several vitamins and minerals in isotonic form, ensuring that your body receives and uses vital nutrients quickly and efficiently. B-vitamins, such as B6, B12 and folic acid, must undergo chemical changes before they can be utilized by the body. Furthermore, different factors, such as age and physical condition, may affect the body's ability to activate vitamins on its own. If the non-active forms are used, the body is forced to work harder to gain the full benefit of the vitamin. These steps are eliminated when the forms used are already in their active states, By utilizing both the activated form of these vitamins, as well as the superior Isotonix delivery system, Isotonix Activated B-complex supports your body's absorption and immediate use of beneficial ingredients.*
A lack of vitamin B in your regimen may impact your physical health in different ways. Hundreds of bodily biochemical reactions are supported by B-vitamins, and deficiency in vitamin B can lead to fatigue and lethargy. A B-complex vitamin is a mixture of eight essential B-vitamins that are critical to metabolism at the cellular level. Isotonix Activated B-complex helps to maintain healthy levels of serotonin, increase energy and decrease stress.*
The Vitamin B Advantage
Isotonix Delivery System
Isotonix - the World's Most Advanced Nutraceuticals
Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
What does “Activated” refer to in Isotonix Activated B-Complex?
Activated refers to the active forms of vitamins B6, B12 and folic acid. Using forms other than these activated forms requires that the vitamins be enzymatically activated prior to utilization by the body. Not only does this take time and energy within the body, there are circumstances in which this reaction is either slowed or inhibited.
What is the source of the vitamin B12 in our Isotonix Activated B-Complex?
Vitamin B-12 comes from bacteria. B12 in our diet can come from eggs or meats, or by taking a supplement. Vegetarians are recommended to take a B vitamin dietary supplement due to their lack of meat intake.
Why are B vitamins so important in the aging process?
B vitamins are important and necessary for numerous metabolic processes within the body. As people age, the ability to absorb vitamins decreases and reduced levels of these vitamins have been associated with impaired cognitive performance. The US RDA's Human Nutrition Center on Aging claims vitamin B12 is the most important nutrient negatively affected by aging. Since vitamin B12 plays a critical role in promoting normal energy production and nervous system function, aging individuals need to make sure they are getting enough vitamin B12 on a daily basis.*
Is it toxic to take too much vitamin B12?
Vitamin B12 has not demonstrated any form of toxicity. As always, we only recommend the product to be taken as directed in the instructions.
Are there any warnings or contraindications for Isotonix Activated B-Complex?
If you are currently taking any prescription drug, have ongoing medical condition, or are pregnant or breastfeeding, you should consult your healthcare provider before using this product. There are no allergens associated with this product.
Methylcobalamin (Vitamin B12) (120 mcg)
Vitamin B12 (cobalamin) is a bacterial product naturally found in animal products, especially organ meats, such as liver, with small amounts derived from peanuts and fermented soy products, such as miso and tempeh. It is essential that vegetarians consume a vitamin B12 supplement to maintain optimal health. Vitamin B12, when ingested, is stored in the liver and other tissues for later use. It supports the maintenance of cells, especially those of the nervous system, bone marrow and intestinal tract. Vitamin B12 is important in homocysteine metabolism (homocysteine is an amino acid that is formed within the body). Normal homocysteine levels are important for maintaining cardiovascular health. Deficiencies of the vitamins folic acid, pyridoxine (B6) or cobalamin (B12) can result in elevated levels of homocysteine. Folate and B12, in their active coenzyme form, are both necessary cofactors for the conversion of homocysteine to methionine, thus helping to maintain healthy blood levels of homocysteine.*
Methylcobalamin is one of the naturally-occurring forms of vitamin B12 found in the human body. The liver must convert cyanocobalamin, the form of B12 most commonly used in supplements, into methylcobalamin, before it can be properly utilized by the body; methylcobalamin is more effective than non-active forms of vitamin B12. Methylcobalamin also assists in the formation of SAMe (S-adenosylmethionine), a nutrient that has powerful mood-elevating properties.*
Folate [as (6S)-5-methyltetrahydrofolic acid, glucosamine salt, Quatrefolic®] (432 mcg)
Folic acid is mainly found in fruits and vegetables. Dark, leafy greens, oranges, orange juice, beans, peas and Brewer’s yeast are the best sources. Folic acid plays a key role by boosting the benefits of B12 supplementation. These two B vitamins join forces and work together in maintaining normal red blood cells. Folic acid assists in the normal utilization of amino acids and proteins, as well as supporting the construction of the material for DNA and RNA synthesis, which is necessary for all bodily functions. Scientific studies have found that when working in tandem with folic acid, B12 is capable of promoting normal homocysteine levels. This works toward supporting a healthy cardiovascular and nervous system.*
Folic acid (folate) must go through a series of chemical conversions before it becomes metabolically active to be properly utilized. Folinic acid is the highly bioavailable, metabolically active derivative of folic acid. It does not require the action of the enzyme dihydrofolinate reductase to become active, so it's not affected by substances and herbs that inhibit this enzyme. Inhibition of this enzyme can result in folic acid deficiency. Some people have a genetic variation (in the MTHRF gene) that reduces the amount of activated folic acid in the body. Folinic acid, unlike folic acid, is not negatively impacted by this genetic variation.*
Quatrefolic® is the glucosamine salt of (6S)-5-methyltetrahydrofolate, the most active form of folate, as it is structurally analogous to the reduced and active form of folic acid. Because this form is naturally present in the body, it is much more bioavailable for its biological action without having to be metabolized in the body. This patented ingredient also provides greater stability and higher water solubility, perfect for Isotonix.*
Riboflavin-5-Phosphate (Vitamin B2) (3 mg)
Vitamin B2 is found in liver, dairy products, dark green vegetables and some types of seafood. Vitamin B2 serves as a coenzyme, working with other B vitamins. It promotes healthy red blood cell formation, supports the nervous system, respiration, antibody production and normal human growth. It supports healthy skin, nails, hair growth and promotes normal thyroid activity (a healthy thyroid is essential in maintaining a healthy weight, among other things). Vitamin B2 supports the body's ability to turn food into energy as a part of the electron transport chain, driving cellular energy on the micro-level. Riboflavin can be useful for pregnant or lactating women, as well as athletes due to their higher caloric needs. Vitamin B2 also promotes the normal breakdown of fats. Vitamin B2 is water-soluble and cannot be stored by the body except in insignificant amounts. It must be replenished daily.*
Pyridoxal-5-Phosphate (Vitamin B6) (6 mg)
Poultry, fish, whole grains and bananas are the main dietary sources of vitamin B6. B6 is a co-factor required for protein and amino acid metabolism, and helps maintain proper fluid balance. It also assists in the maintenance of healthy red and white blood cells, which keeps our body healthy. Vitamin B6 promotes normal hemoglobin synthesis (hemoglobin is the protein portion of red blood cells which carries oxygen throughout the body). Because vitamin B6 is involved in the synthesis of neurotransmitters in the brain and nerve cells, it has been recommended as a nutrient to support mental function, specifically mood. Athletic supplements often include vitamin B6 because it promotes the conversion of glycogen to glucose for energy in muscle tissue. Vitamin B6, when taken with folic acid, has been shown to help maintain normal plasma levels of homocysteine, which promotes optimal cardiovascular health. Vitamin B6 should be administered as a part of a complex of other B vitamins for best results.*
Magnesium (Carbonate) (40 mg)
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green, leafy vegetables are potent sources of magnesium because of their chlorophyll content. Meats, starches, milk, refined and processed foods contain low amounts of magnesium. Recent research shows that many American diets are magnesium deficient.*
Magnesium is a component of the mineralized part of bone, and promotes the normal metabolism of potassium and calcium in adults. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It also supports the transportation of calcium inside the cell for utilization. Magnesium promotes the normal functioning of muscle and nervous tissue, and the synthesis of all proteins, nucleic acids, nucleotides, fats and carbohydrates.*
Magnesium supports the normal release of energy from food during metabolism, regulation of body temperature, proper nerve function and helping the body handle stress. Importantly, magnesium also promotes healthy bones, teeth and normal muscle development. It works together with calcium and vitamin D to promote strong bones. Magnesium, when combined with calcium, helps support the heart muscle in maintaining a regular heartbeat and promoting normal blood pressure.*
Potassium (Bicarbonate) (94 mg)
Potassium is an electrolyte stored in the muscles. Foods rich in potassium include bananas, oranges, cantaloupe, avocado, raw spinach, cabbage and celery. Potassium is an essential macromineral that helps maintain fluid balance in the body. It also plays a role in a wide variety of biochemical and physiological processes. Among other things, potassium promotes the transmission of nerve impulses, the contraction of cardiac, skeletal and smooth muscle, the production of energy, the synthesis of nucleic acids and the maintenance of normal blood pressure.*
In 1928, it was first suggested that high potassium intake could help maintain cardiovascular health. Potassium promotes normal muscle relaxation and helps maintain normal insulin release. It also promotes glycogen and protein synthesis. Potassium is an electrolyte that promotes normal heartbeat. Potassium promotes the normal release of energy from protein, fat and carbohydrates during metabolism. Potassium helps maintain normal water balance, supports recovery from exercise and the elimination of wastes. Sodium and potassium are two of the most important ions in maintaining the homeostatic equilibrium of the body fluids.*
Thiamin HCl (Vitamin B1) (2 mg)
Thiamin promotes normal carbohydrate metabolism and nerve function. Thiamin is required for a healthy nervous system, and supports the production of certain neurotransmitters which have an important role in muscle function. It supports the digestive process, increases energy and helps promote mental clarity.*
D-Calcium Pantothenate (Vitamin B5) (20 mg)
Pantothenic acid (B5) promotes proper neurotransmitter activity in the brain. Pantothenic acid is also known as the anti-stress vitamin because it helps relieve physical and emotional stress, and promotes the secretion of hormones essential for optimal health.*
Niacinamide (Vitamin B3) (20 mg)
Niacin is a water-soluble vitamin necessary for many aspects of health, growth and reproduction. Niacin supports the proper functioning of the digestive system, skin and nerves. It promotes the conversion of food to energy. Niacin is found in dairy products, poultry, fish, lean meats, nuts, eggs, legumes, and enriched breads and cereals.*
Biotin (Vitamin B7) (300 mcg)
Biotin can be found in food sources, such as egg yolks, peanuts, beef liver, milk, cereals, almonds and Brewer’s yeast. Biotin promotes healthy cell growth, the production of fatty acids, metabolism of fats and amino acids. It supports the citric acid cycle, which is the process in which energy is generated during exercise. Biotin is also helpful in maintaining steady blood sugar levels. Biotin is often recommended for maintaining strong hair and nails.*
These 10 ingredients, combined with the superior delivery of Isotonix®, create a powerhouse B vitamin product superior to the rest on the market. Isotonix Activated B-Complex delivers all of the B vitamins along with select minerals and electrolytes to help boost energy, decrease stress, improve mood, and much more. The activated forms of select vitamins ensure maximal utilization by the body for optimal results.*
- Benton D., et al. Thiamine supplementation for mood and cognitive functioning. Psychopharmacology. 129(1):66-71, 1997.
- Benton, D., et al. The effects of nutrients on mood. Public Health Nutr. 2(3A):403-409, 1999.
- Bhagavan, H. N., et al. The effect of pyridoxine hydrochloride on blood serotonin and pyridoxal phosphate contents in hyperactive children. Pediatrics. 55(3):437-441, 1975.
- Bronstrup A, Hages M, Prinz-Langenohl R, Pietrzik K. Effects of folic acid and
- Bryan, J., et al. Associations between dietary intake of folate and vitamins B-12 and B-6 and self-reported cognitive function and psychological well-being in Australian men and women in midlife. J Nutr Health Aging. 8(4):226-232, 2004.
- Bryan, J., et al. Short-term folate, vitamin B-12 or vitamin B-6 supplementation slightly affects memory performance but not mood in women of various ages. Journal of Nutrition. 132(6):1345-1356, 2002.
- combinations of folic acid and vitamin B12 on plasma homocysteine concentrations in healthy young women. Am J Clin Nutr 68:1104-10, 1998.
- Coppen, A., et al. Plasma folate and affective morbidity during long-term lithium therapy. Br J Psychiatry. 141:87-89, 1982.
- Cummings, P. M., et al. Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease. J Am Coll Cardiol. 36:758-765, 2000.
- Dharmarajan, T. S., et al. Vitamin B12 deficiency. Recognizing subtle symptoms in older adults. Geriatrics. 58(3):30-34, 2003.
- Doshi, S. N., et al. Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering. Circulation. 105(1):22-26, 2002.
- Duthie, S. J., et al. Homocysteine, B vitamin status, and cognitive function in the elderly. American Journal of Clinical Nutrition. 75(5):908-913, 2002.
- Friso, S., et al. Low plasma vitamin B-6 concentrations and modulation of coronary artery disease risk. Am J Clin Nutr. 79(6):992-998, 2004.
- Grant, J. E., et al. Analysis of dietary intake and selected nutrient concentrations in patients with chronic fatigue syndrome. J Am Diet Assoc. 96(4):383-386, 1996.
- Hartvig, P., et al. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with position emission tomography. Neural Trans. 102:91-97, 1995.
- Heap, L. C., et al. Vitamin B status in patients with chronic fatigue syndrome. J R Soc Med. 92(4):183-185, 1999.
- Heseker, H., et al. Psychological disorders as early symptoms of a mild-to-moderate vitamin deficiency. Ann N Y Acad Sci. 669:352-357, 1992.
- Jacobson, W., et al. Serum folate and chronic fatigue syndrome. Neurology. 43:2645-2647, 1993.
- Kelly, G. S. Nutritional and botanical interventions to assist with the adaptation to stress. Alternative Medicine Review.4(4):249-265, 1999.
- Litoff, D., et al. Effects of pantothenic acid supplementation on human exercise. Med Sci Sport Exercise., 17(Supplement):287, 1985.
- Osada, K., et al. Experimental study of fatigue provoked by biotin deficiency in mice. Int J Vitam Nutr Res. 74(5):334-340, 2004.
- Quadri, P., et al. Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia. Am J Clin Nutr. 80(1):114-122, 2004.
- Riggs, K. M., et al. Relations of vitamin B-12, vitamin B-6, folate, and homocysteine to cognitive performance in the Normative Aging Study. American Journal of Clinical Nutrition. 63(3):306-314, 1996.
- Van den Berg M., et al. Combined vitamin B-6 plus folic acid therapy in young patients with arteriosclerosis and hyperhomocysteinemia. Journal Vascular Surgery. 20(6):933-940, 1994.
- van Oort FV, Melse-Boonstra A, Brouwer IA, et al. Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study. 77:1318-23, 2003.
- Vargiu, R., et al. Enhancement of muscular performance by a coformulation of propionyl-L-carnitine, coenzyme Q(10), nicotinamide, riboflavin and pantothenic acid in the rat. Physiol Behav. 76(2):257-63, 2002.
- Wald DS, Bishop L, Wald NJ, et al. Randomized trial of folic acid supplementation and serum homocysteine levels. Arch Intern Med 61:695-700, 2001.
- Werbach, M. R. Nutritional strategies for treating chronic fatigue syndrome. Alternative Medicine Review. 5(2):93-108, 2000.
- Woo, K. S., et al. Long-term improvement in homocysteine levels and arterial endothelial function after 1-year folic acid supplementation. American Journal of Medicine. 112(7):535-539, 2002.
This product is great it gives you energy
Makes you feel great all day!
- Shop Consultant
give me more energy
This product has helped me in keeping up with my health.
dissolves instantly in water
Like all vitamins, the taste is unique - but it instantly dissolves in water and the benefits outweigh something like liquid fizzy gummy bears.
- Shop Consultant
My body can use these B vitamins
I did a genetic test that showed I don't break down B vitamins very well in my system. Because these are activated, my body can use them. I take one in the morning and one in the afternoon - more if more stress. It helps a lot.