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Reset, Rebuild and Restore Three Products - Three Simple Steps OPC-3® for Oxygen Delivery Prime NAD+ for Cell Renewal Magnesium for Quality Sleep

by: Isotonix®

$119.95 - $149.95

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  • Maximum Effect. Amazing Results. A New You with Core 3 Health.

    Discover the revitalizing synergy of these three powerhouse products, used in three simple steps! 

    Isotonix OPC-3®. The world’s most powerful antioxidant, for oxygen delivery, glowing skin and a surge of vitality. 

    Prime Anti-Aging Nutraceuticals® NAD+. Renews cells and DNA integrity, mental sharpness and feeling youthful. 

    Isotonix® Magnesium. Stress-busting, sleep-enhancing, heart-strengthening and energy-activating.

  • Isotonix OPC-3 Active Ingredients: Grape seed extract, Pycnogenol® (pine park extract), red wine extract, bilberry extract, citrus bioflavonoid complex 

    Other ingredients: Fructose, glucose, citric acid, potassium bicarbonate, maltodextrin, silica, calcium sulfate, food starch (modified), apple pectin, stearic acid. 

    Prime NAD+ Active Ingredients: Crystalline nicotinamide riboside chloride, pterostilbene 

    Other Ingredients: Vegetarian capsule (hypromellose), microcroystalline cellulose, vegetable magnesium stearate, silicon dioxide

    Isotonix Magnesium Active Ingredients: Magnesium (citrate and glycinate) 

    Other Ingredients: Fructose, malic acid, citric acid, orange juice powder, potassium bicarbonate, orange flavor, passionfruit flavor, silicon dioxide, rebaudioside A (stevia leaf), luo han guo fruit extract, stearic acid

Triple Threat Daily Regimen

Isotonix OPC-3

95% intestinal nutrient delivery for max absorption

Isotonix Magnesium

Support 300+ enzyme systems

Prime NAD+

The secret to healthy aging

image of pine bark

Includes our top seller, Isotonix OPC-3

The super antioxidant in OPC-3, pine bark extract (Pycnogenol®)
Isotonix OPC-3 contains the only isotonic form of Pycnogenol®, is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and powerful bioflavonoids in the world.

Product Classifications

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Vegan

Image of wheat with a line through it

Gluten-Free

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No Detectable GMO

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Good Manufacturing Practices

Directions for Use

image of one capful Isotonix OPC-3 and one capful Isotonix Magnesium

Step 1 (Morning): Take Isotonix OPC-3 and the first capful of Isotonix Magnesium when you wake up.

image of canister of Prime NAD+

Step 2 (Midday): Take Prime NAD+ before your midday meal.

image of one capful of Isotonix Magnesium with the product bottle

Step 3 (Evening): Take the second capful of Isotonix Magnesium before you go to bed.

Key Ingredients & Their Benefits

image of pine bark
Isotonix OPC-3®: Pycnogenol®‡, Pine Bark Extract*

Supports the normal dilation of blood vessels

Provides complete antioxidant protection

Combats free radicals

Supports a healthy complexion

Promotes healthy sperm quality

image of blueberries against a blue background
Isotonix OPC-3®: Bilberry Extract*

Powerful antioxidant

Supports healthy vision

Maintains healthy circulation

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Isotonix® Magnesium: Magnesium (Citrate & Glycinate)*

Helps the body maintain a healthy level of magnesium, combatting magnesium deficiency

Promotes muscle health and comfort

Supports a healthy sleep quality

Promotes bone health

image of magnified cells
Prime Anti-Aging Nutraceuticals® NAD+: Nicotinamide Riboside (crystalline nicotinamide riboside chloride)*

Supports healthy NAD production 

Combat the cellular aging process 

Promotes normal activity of the SIRT-1 gene 

Supports cellular health and metabolism 

Revitalize Your Body With Core 3 Health

Restore, rebuild and reset with Core 3 Health: three powerful products in three simple steps. Our hottest health superstars have been carefully selected for one triple-threat system for maximum effect and truly amazing results.

Frequently Asked Questions

  • Take Isotonix OPC-3 and Isotonix Magnesium in the morning. Take Prime NAD+ 4–5 hours later, then another serving of Isotonix Magnesium before bed. This 1-2-3 system supports metabolic health and sleep.

  • The sugars make the solution isotonic, enhancing nutrient absorption into the bloodstream and optimizing the delivery of nutrients to target cells.

  • Yes, follow the 1-2-3 schedule based on your sleep cycle. Take Isotonix OPC-3 and Magnesium when you wake up, Prime NAD+ 4-5 hours later and Magnesium before bed.

  • Isotonix OPC-3 is delivered in an isotonic form for quick absorption. It combines powerful antioxidants like Pycnogenol®, bilberry, and grape seed extracts, supporting cardiovascular health, joint flexibility, and free radical protection.

  • Isotonix Magnesium provides 400 mg of highly bioavailable magnesium forms (glycinate and citrate), supporting brain function, muscle health, and stress management.

  • Prime NAD+ supports NAD+ levels with 250 mg of nicotinamide riboside (NR) and 50 mg of pterostilbene, supporting cellular regeneration, mitochondrial health, and DNA integrity.

Research Scope on Core 3 Health

view full Reference List

100

The number of active compounds found in Red Wine Extract

30+

trillion cells in the body are fueled by the NAD molecule

300

Magnesium supports more than 300 enzyme systems

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

Reviews


Customer Reviews
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Displaying reviews 1 - 5 of 64

by AngelicaG

Question?

How often do I have to take every day?

Response from Customer Service:

Thank you for your question and for choosing Core 3 Health! We recommend following the directions on each product’s label for best results. For your convenience, detailed steps are also provided on the Core 3 Health product page—if you scroll down, you’ll find the daily routine outlined:

Step 1 (Morning): Take Isotonix OPC-3 and the first capful of Isotonix Magnesium when you wake up.

Step 2 (Midday): Take Prime NAD+ before your midday meal.

Step 3 (Evening): Take the second capful of Isotonix Magnesium before you go to bed.

If you have any more questions or need additional guidance, please let us know. We're here to help!

by LindaC

Fructose

Love the products but would rather have them without fructose

Response from Customer Service:

Thank you so much for your feedback on Isotonix® Multimineral! We’re glad to hear that you love the products. We understand your concern about fructose, and want you to know that, for the product to be truly isotonic, fructose is needed as part of the formula. We appreciate your suggestion and will inform the appropriate team of your feedback for their consideration. Thank you for being a valued member of our community!

by Anonymous

LOVE

These products are wonderful.
I am 95 years old. And they give me plenty of energy. ❤️

Response from Customer Service:

Thank you so much for your inspiring review! We're delighted to hear that Core 3 Health products are supporting your energy and well-being at 95. Your experience is truly motivating, and we’re honored to be a part of your wellness routine. Wishing you continued health and vitality!

by ernestN

  • Shop Consultant
Isotonix Ultimate Health and Energy

Isotonix is not just a game changer, it's a life changer. More energy and endurance. Recover faster and heal faster.
Can't wait to spread the word.

Response from Customer Service:

Thank you so much for your wonderful review and enthusiasm for Core 3 Health! We're thrilled to hear that you’ve experienced such a positive change in your energy and endurance. Your excitement to share your experience with others truly means a lot to us. Thank you for being a valued part of our community and for helping inspire others on their wellness journey!

by MarleneR

  • Shop Consultant
Love is in the Air

I Love these products and Market America has
wrapped these products in a bundle that makes
it easy to stay ahead of the process of never running
out of any of them!

Marlene J. Rydingsword

Response from Customer Service:

Thank you so much for your wonderful review of Core 3 Health! We’re delighted to hear how much you love the products and that the bundled option makes it easy for you to stay on top of your routine.

Your feedback means a lot to us, and we’re grateful to be part of your wellness journey. If you ever have any suggestions or need support, we’re always here to help. Thank you for choosing Core 3 Health and for being part of the Market America family!