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World's Most Powerful Antioxidant Bestseller for Over 30 Years Only Isotonic Pycnogenol® in the World 18 Million Sold Worldwide

by: Isotonix®

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  • Feel Young and Stay Healthy with Isotonix OPC-3®

    Results matter. With the unmatched 95% nutrient delivery of Isotonix OPC-3®, feel the life-changing difference in your energy, muscles and joint performance. 

    Powered by Pycnogenol®—nature’s most powerful antioxidant—this formula aids oxygen delivery, fuels vital organs and combats signs of aging. Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed for your health and longevity!

  • Active Ingredients: Grape seed extract, pine bark extract (Pycnogenol®), red wine extract, bilberry extract, citrus bioflavonoid complex

    Other ingredients: Fructose, glucose, citric acid, potassium bicarbonate, maltodextrin, silica, calcium sulfate, food starch (modified), apple pectin, stearic acid.   

Formulated as the best antioxidant

Validated by research

20x

stronger than vitamin C

50x

stronger than vitamin E

95%

intestinal nutrient delivery for max absorption

image of pinetree bark

The Super Antioxidant in OPC-3, Pycnogenol®‡

Isotonix OPC-3 contains the only isotonic form of Pycnogenol® in the world. Pycnogenol® is a natural plant extract from the bark of the French maritime pine tree and the most clinically researched and potent bioflavonoid.

Product Classifications

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Gluten-Free

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No Detectable GMO

image of glass containing liquid

Isotonic

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Vegan

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Good Manufacturing Practices

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Dairy Free

Directions for Use

Image of person pouring one level cap of Isotonix powder into cup

Pour 1 small capful (3.3 g) of powder into a cup.

Image of mixed Isotonix OPC-3 with water in cup.

Add water 2 fl. oz/60 mL of water for each capful and stir.

image of a woman holding a cup with mixed Isotonix OPC-3

Enjoy once a day. For maximum absorption take on an empty stomach.

Key Ingredients & Their Benefits

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Grape Seed Extract*

Maintains healthy cholesterol levels

image of red wine in a wooden spoon
Red Wine Extract*

Powerful antioxidant

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Bilberry Extract*

Powerful antioxidant

Supports healthy vision

Maintains healthy circulation

image of citrus fruits against a purple background
Citrus Extract (Bioflavaniods)*

Promotes cardiovascular health

Maintains healthy circulation

image of pine bark
Pycnogenol®‡, Pine Bark Extract*

Supports the normal dilation of blood vessels

Provides complete antioxidant protection

Combats free radicals

Supports a healthy complexion

Promotes healthy sperm quality

World's Most Powerful Antioxidant

Outperforming any conventional antioxidant on the market, discover this ultimate supplement designed to supercharge health and longevity!

:05 minutes

Isotonix Liquid Vitamins

  • Formulated to survive digestion.
  • Delivers concentrated nutrients to the site of absorption.
  • Contains no fillers or binders.
  • No artificial color or flavors. 


:40 minutes

Standard Vitamin Tablet

  • Contains lab-created coatings and lubricants.
  • Often contains artificial colors, nutrients and flavors.
  • Limited absorption of nutrient utilization. 

Frequently Asked Questions

  • Isotonix OPC-3 contains bioflavonoids, plant compounds that support cardiovascular health, healthy circulation and skin, joint and tissue integrity; it uses a unique Isotonix delivery system for fast, effective absorption and includes scientifically proven antioxidants to fight free radicals, making it one of the most powerful products available.

  • Thanks to its liquid, isotonic form, Isotonix OPC-3 is absorbed quickly by the small intestine, entering the bloodstream within minutes; this rapid absorption allows the body to benefit almost immediately.

  • Free radicals cause oxidative stress, which contributes to aging, circulation and heart and immune health. OPCs are powerful antioxidants — with more staying power than vitamins C and E — that help neutralize free radicals. Taking OPC-3 daily is essential for combating free radical damage and promoting health.

  • Even athletes experience free radical damage from increased oxygen use during exercise, which can affect muscle performance and endurance. Studies show OPCs promote endurance, reduce mild muscle cramps and support healthy blood flow, helping muscles recover and perform.

  • Yes, studies show OPCs can help mensural cramps.

  • Pycnogenol® is a patented extract from French maritime pine bark, supported by over 120 clinical studies; it acts as a powerful antioxidant, helping maintain healthy circulation, blood pressure and blood vessel function by promoting nitric oxide production.

Research Scope on OPC-3

view full Reference List

558+

Studies on Pycnogenol® and Human Health

100

The number of active compounds found in Red Wine Extract

3

Independent studies for Isotonix OPC-3®

4x

The bioavailability of Isotonix OPC-3® compared to a tablet form

*These statements have not been evaluated by the Food and Drug Administration. This product(s) is not intended to diagnose, treat, cure or prevent any disease.

As Pycnogenol®. Pycnogenol is a registered trademark of Horphag Research Ltd. Use of this product may be protected by one or more U.S. patents and other international patents.

Reviews


Customer Reviews
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Displaying reviews 1 - 5 of 382

by JanetM

Love the product but really dislike the packaging

Have been using this for years and really like it. However, a while back the packaging changed from the plastic cup that fit tightly over the bottle lid to the current white top that fits loosely over the lid. The new top doesn’t keep the powder dry & it clumps something awful. Have had to throw some of it out because it was so clumped & I keep it in a dry cupboard. Very unhappy with the current packaging..

Response from Customer Service:

Thank you so much for taking the time to share your feedback and for being a loyal user of Isotonix OPC-3® for so many years. We’re glad to hear how much you like the product itself, and we truly appreciate you letting us know about your concerns with the new packaging. Your experience with the lid and product clumping is important for us to know, and we will be sure to inform our product managers of your feedback. Thank you again for bringing this to our attention, we value your input as it helps us improve our products and your experience.

by DavidW

Good product

My wife and I have been taking OPC-3 for several years. She has an auto immune condition and a coworker of hers recommended she take it and I’ve joined her as part of our morning routine

Response from Customer Service:

Thank you so much for taking the time to share your experience with Isotonix OPC-3®! We’re delighted to hear that it has become a regular part of your morning routine. Your feedback is greatly appreciated, and we’re grateful for your continued support over the years. If you have any questions or suggestions, please don’t hesitate to let us know. Thank you again!

by RobinH

Good Product

I have been taking this product for 2 months, and can tell a difference. More energy, and fewer mood swings.

Thank You

Response from Customer Service:

Thank you so much for sharing your feedback on Isotonix OPC-3® for Adults & Children Ages 4+. We're glad to hear you've noticed a positive difference, including more energy and improved mood. Your experience means a lot to us, and we appreciate you taking the time to let us know how our product fits into your routine. If you have any questions or suggestions, please feel free to reach out. Thank you for being a valued member of our community!

by FranceneP

  • Shop Consultant
Since 1997!

I have been using OPC-3 since 1997 and it is wonderful. Back then there was a short black-and-white video that distributors could use that showed the blood before and after using OPC. Before, clumpy and chain-y, after blood cells separated, white blood cells not stuck in some of the clumps, all flowing smoothly. Six months after starting OPC, I had the opportunity to see how my blood was going under a microscope. Guess what? It was blood cells separated, white blood cells floating free to do their work. I have a testimony that this product does what it is claimed to do.

Response from Customer Service:

Thank you so much for sharing your long-term experience and history with the Isotonix OPC-3® for Adults & Children Ages 4+! It means a lot that you’ve been using it since 1997 and continue to value it. We truly appreciate your loyalty and the time you took to describe your journey with the product.

by Anonymous

So far so good.

I took this product years ago and I remember feeling great I’ve recently started taking it again.

Response from Customer Service:

Thank you so much for sharing your experience! We’re glad to hear you’ve returned to Isotonix OPC-3® and that you remember feeling great while using it. We appreciate your trust in our product and are happy to be part of your wellness journey once again!