H2TAB Molecular Hydrogen Tablets

• Aokia, K., Nakao, A., Adachi, T., Matsui, Y., & Miyakawa, S. (2012). Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes. Medical Gas Research, 2, 12.
• Bittner, A. C., Bittner, R. C. L., Lile, Jr., K., & Sakuragi, Y. (2007). Intra-individual ergonomics (I2E): Performance effects of ultra-negative-ion water.
• Da Ponte, A., Giovanelli, N., Nigris, D., & Lazzer, S. (2017). Effects of hydrogen rich water on prolonged intermittent exercise. The Journal of Sports Medicine and Physical Fitness, 58(5): 612–621. 
• Darinka Korovljev, Dejan Javorac, Nikola Todorovic, Marijana Ranisavljev, Dagrun Engeset, Tonje Holte Stea, Jelena Ostojic, Katarina Bijelic, Branislava Srdjenovic Conic, Nebojsa Kladar, Laszlo Ratgeber, Nenad Trunic, Sava Rajkovic, Valdemar Stajer and Sergej M. Ostojic The Effects of 12-Week Hydrogen-Rich Water Intake on Body Composition, Short-Chain Fatty Acids Turnover, and Brain Metabolism in Overweight Adults: A Randomized Controlled Trial
• Dixon, B. J., Tang, J., & Zhang, J. H. (2013). The evolution of molecular hydrogen: A noteworthy potential therapy with clinical significance. Medical Gas Research, 3(1): 10.
• Drid, P., Stojanovic, M. D.M., Trivic, T., & Ostojic, S. M. (2016). Molecular hydrogen affected post-exercise recovery in judo athletes. Medicine & Science in Sports & Exercise, 48(5S): 1071
• Drid, P., Trivic, T., Casals, C., Trivic, S., Stojanovic, M., & Ostojic, S. M. (2016). Is molecular hydrogen beneficial to enhance post-exercise recovery in female athletes? Science & Sports. 
• Hiraoka, A., Sasaki, S., Yamada, T., Shinohara, A., & Chiba, M. (2006). Effects of drinking a water product with anti-oxidant activities in vitro on the blood levels of biomarker substances for the oxidative stress. Journal of Health Science, 52(6): 817–820.
• Hiraoka, A., Sasaki, S., Yamada, T., Shinohara, A., & Chiba, M. (2006). Effects of drinking a water product with anti-oxidant activities in vitro on the blood levels of biomarker substances for the oxidative stress. Journal of Health Science, 52(6): 817–820.
• Ichihara, M., Sobue, S., Ito, M., Ito, M., Hirayama, M., & Ohno, K. (2015). Beneficial biological effects and the underlying mechanisms of molecular hydrogen — Comprehensive review of 321 original articles. Medical Gas Research, 5: 12.
• Ito, H., Kabayma, S., & Goto, K. (2020).Ito, H., Kabayma, S., & Goto, K. (2020).Effects of electrolyzed hydrogen water ingestion during endurance exercise in a heated environment on body fluid balance and exercise performance. Temperature, 7(3): 290–299.
• Korovljev D, Ostojic J, Todorovic N, Ostojic SM. Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans. Arch Med Sci. 2023 Jul 13;19(4):1151-1153. doi: 10.5114/aoms/162938. PMID: 37560746; PMCID: PMC10408004.
• LeBaron T., Kharman J., McCullough M. (2021). Effects of an H2-infused, Nitric Oxide-Producing Functional Beverage on Exercise and Cognitive Performance. Journal of Science and Medicine; 3(2):1-15
• Li Chen. (2015). Hydrogen rich-water on blood lactic acid after repeated exhaustive exercise. Journal of Taishan Medical College. * IN CHINESE, ENGLISH ABSTRACT AVAILABLE
• Li Y, Bing R, Liu M, Shang Z, Huang Y, Zhou K, Bao D, Zhou J. Can molecular hydrogen supplementation reduce exercise-induced oxidative stress in healthy adults? A systematic review and meta-analysis. Front Nutr. 2024 Mar 25;11:1328705. doi: 10.3389/fnut.2024.1328705. PMID: 38590828; PMCID: PMC10999621.
• Minghao, et al. (2017). Effects of hydrogen-rich water on antioxidant capacity in female judo athletes in training. Chin J Sports Med.*
• Moradi, B., Saberi, E., Hasani, & A., Saheb, A. M. The role of drinking hydrogen-rich water produced by alkaline stick on resistance exercise in athletes.
• Ostojic, S. (2011). Drinks with alkaline negative oxidative reduction potential improve exercise performance in physically active men and women: Double-blind, randomized, placebo-controlled, cross-over trial of efficacy and safety. Serbian Journal of Sports Sciences, 5(3): 83–89.
• Ostojic, S. M. (2012). Serum alkalinization and hydrogen-rich water in healthy men. Mayo Clinic Proceedings, 87(5): 501–502.
• Ostojic, S. M., & Stojanovic, M. D. (2012). Hydrogen-rich water affected blood alkalinity in physically active men. Research in Sports Medicine, 22(1): 49–60.
• Ostojic, S., Korovljev, D., Stajer, V., & Javorac, D. (2018). 28-days hydrogen-rich water supplementation affects exercise capacity in mid-age overweight women. Medicine & Science in Sports & Exercise, 50(5S): 728–729. 
• Sha, J.-B., Zhang, S.-S., Lu, Y.-M., Gong, W.-J., Jiang, X.-P., Wang, J.-J., Qiao, T.-L., Zhang, H.-H., Zhao, M.-Q., Wang, D.-P., Xia, H., Li, Z.-W., Chen, J.-L., Zhang, L., & Zhang, C.-G. (2018). Effects of the long-term consumption of hydrogen-rich water on the antioxidant activity and the gut flora in female juvenile soccer players from Suzhou, China. Medical Gas Research, 8(4): 135–143. 
• Shibayama, Y.; Takeuchi, K., Dobashi, S., & Koyama, K. (2017). Hydrogen-rich water modulates redox status repeated three consecutive days of strenuous exercise. Medicine & Science inMedicine & Science inSports & Exercise, 49(5S): 941.
• Sun, Y.-P. & Sun, L. 2017. Selective protective effect of hydrogen water on free radical injury of athletes after high-intensity exercise. Biomedical Research, 28(10).  
• Tanaka, Y., Saihara, Y., Izumotani, K., & Nakamura, H. (2018). Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. Medical Gas Research, 8(4): 160–166.
• Tashiro, H., Hokudo, T., Ono, H., Fujiyama, Y., & Baba, T. (2000). Clinical evaluation of alkaline ionized water for abdominal complaints: Placebo controlled double blind tests. Digestion & Absorption.
• Timón, R., Olcina, G., González-Custodio, A., Camacho-Cardenosa, M., Camacho-Cardenosa, A., & Martínez Guardado, I. (2021). Effects of 7-day intake of hydrogen-rich water on physical performance of trained and untrained subjects. Biology of Sport 38(2): 269–275
• Todorovic N, Fernández-Landa J, Santibañez A, Kura B, Stajer V, Korovljev D, Ostojic SM. The Effects of Hydrogen-Rich Water on Blood Lipid Profiles in Clinical Populations: A Systematic Review and Meta-Analysis. Pharmaceuticals. 2023; 16(2):142. https://doi.org/10.3390/ph16020142
• Trivic, T., Vojnovic, M., Drid, P., & Ostojic, S. M. (2017). Drinking hydrogen-rich water for 4 weeks positively affects serum antioxidant enzymes in healthy men: A pilot study. Current Topics in Nutraceutical Research, 15(1).
• Valdemar Stajer, Nikola Todorovic, Branislava Sr?enovi? ?oni?, Nebojsa Kladar, Dagrun Engeset, Tonje Holte Stea, Laszlo Ratgeber, Jozsef Betlehem, Pongrac Acs, Scott C. Forbes, Darren G. Candow and Se
• Wu, P. (2020). Hydrogen-rich water improves the physical ability of football players and the anti-fatigue ability of rats, Revista Cientifica, 30(1): 428-435.
• Yang, E. J., Kim, J. R., Ryang, Y. S., Kim, D. H., Deung, Y. K., Park, S. K., & Lee, K. J. (2007). A clinical trial of orally administered alkaline reduced water.
• YU Yang, ZHAO Yun-Lai, SONG Guo-Hua, QIN Shu-Cun. The effects of hydrogen-oxygen mixed gas on skin blood flow in healthy adults[J]. Editorial Office of Chinese Journal of Arteriosclerosis, 2018, 26(6):557-560.
• Lv, X., Lu, Y., Ding, G., Li, X., Xu, X., Zhang, A., & Song, G. (2022). Hydrogen intake relieves alcohol consumption and hangover symptoms in healthy adults: a randomized and placebo-controlled crossover study. American Journal of Clinical Nutrition, 116(5), 1208–1218. https://doi.org/10.1093/ajcn/nqac261
• Takamitsu Shinada et al. Effects of Natural Reduced Water on Cognitive Function, Body Composition, and Psychological Function in Older Adults: Study Protocol for a Randomized Controlled Trial. Methods Protoc. 2021, 4(4), 73. 
• Fujita K, Seike T, Yutsudo N, Ohno M, Yamada H, Yamaguchi H, et al. (2009) Hydrogen in Drinking Water Reduces Dopaminergic Neuronal Loss in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine Mouse Model of Parkinson's Disease. PLoS ONE 4(9): e7247 
• Korovljev D, Ostojic J, Todorovic N, Ostojic SM. Molecular hydrogen modulates brain glutamate/GABA-glutamine cycle in overweight humans. Arch Med Sci. 2023 Jul 13;19(4):1151-1153.
• Trivic, T., Vojnovic, M., Drid, P., & Ostojic, S. M. (2017). Drinking hydrogen-rich water for 4 weeks positively affects serum antioxidant enzymes in healthy men: A pilot study. Current Topics in Nutraceutical Research, 15(1).
• AHiraoka, A., Sasaki, S., Yamada, T., Shinohara, A., & Chiba, M. (2006). Effects of drinking a water product with anti-oxidant activities in vitro on the blood levels of biomarker substances for the oxidative stress. Journal of Health Science, 52(6): 817–820.
• Zhou, Q., Li, H., Zhang, Y., Zhao, Y., Wang, C., & Liu, C. (2024). Hydrogen-Rich Water to Enhance Exercise Performance: A Review of Effects and Mechanisms. Metabolites, 14(10), 537. https://doi.org/10.3390/metabo14100537
• Sládečková B, Botek M, Krejčí J, Valenta M, McKune A, Neuls F and Klimešová I (2024), Hydrogen-rich water supplementation promotes muscular recovery after two strenuous training sessions performed on the same day in elite fin swimmers: randomized, double-blind, placebo-controlled, crossover trial. Front. Physiol. doi: 10.3389/fphys.2024.1321160

Isotonix Daily Essentials Packets

Isotonix OPC-3®

• Devaraj, S., et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 37:931-4, 2002.
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• Freedman, J., et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation 103:2792-8, 2001.
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• Monograph. Vaccinium myrtillus (bilberry). Altern Med Rev 6:500-4, 2001.
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• Nuttall SL, Kendall MJ, Bombardelli E, Morazzoni P. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther 23: 385-89, 1998.
• Packer, L., et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med 27:704-24, 1999. Review.
• Schönlau, F., et al. The cosmeceutical Pycnogenol®. J Appl Cosmetology 20: 241-6, 2002.
• Segger, D. and Schönlau, F. Supplementation with Evelle® improves skin smoothness and elasticity in a double blind, placebo-controlled study with 62 women. Journal of Dermatological Treatment 15:222-26, 2004.
• Shi, J., et al. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6:291-9, 2003. Review.
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• Watson, R. Pycnogenol® and cardiovascular health. Evidence-Based Integrative Medicine 1: 27-32, 2003.
• Ames, BN, et al. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 90:7915-7922, 1993.
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• Wilson D et al. A randomized, double-blind, placebo-controlled exploratory study to evaluate the potential of pycnogenol for improving allergic rhinitis symptoms. Phytother Res. 24(8):1115-9, 2010.
• Lau B et al. Pycnogenol as an adjunct in the management of childhood asthma. J Asthma. 41(8):825-32, 2004.
• Choi YH, Yan GH. Pycnogenol inhibits immunoglobulin E-mediated allergic response in mast cells. Phytother Res 23: 1691-1695, 2009.
• Sharma SC, Sharma S, Gulati OP. Pycnogenol® inhibits the release of histamine from mast cells. Phytother Res, 17: 66-69, 2003.
• Hosseini S, Pishnamazi S, Sadrzadeh MH, Farid F, Farid R, Watson RR. Pycnogenol® in the management of asthma. J Med Food 4: 201-209, 2001.

Isotonix® Multivitamin

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• Anderson RA. Effects of chromium on body composition and weight loss. Nutr Rev. 1998 Sep;56(9):266-70.
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• Baxter GF, Sumeray MS, Walker JM. Infant size and magnesium: insights into LIMIT-2 and ISIS-4 from experimental studies. Lancet. 1996; 348:1424-1426.
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• Buchinger W, Lorenz-Wawschinek O, Semlitsch G, Langsteger W, Binter G, Bonelli RM, Eber O. Thyrotropin and thyroglobulin as an index of optimal iodine intake: correlation with iodine excretion of 39,913 euthyroid patients. Thyroid. 1997 Aug;7(4):593-7.
• Butterfield DA, Koppal T, Subramaniam R, Yatin S. Vitamin E as an antioxidant/free radical scavenger against amyloid beta-peptide-induced oxidative stress in neocortical synaptosomal membranes and hippocampal neurons in culture: insights into Alzheimer's disease. Rev Neurosci. 1999;10(2):141-9
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• de Lourdes Lima M, Cruz T, Carreiro Pousada J, et al. The effect of magnesium supplementation in increasing doses on the control of type 2 diabetes. Diabetes Care. 1998; 21:682-686.
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• Facchinetti F, Borella P, Sances G, et al. Oral magnesium successfully relieves premenstrual mood changes. Obstet Gynecol. 1991; 78:177-181.
• Facchinetti F, Borella P, Sances G, et al. Oral magnesium successfully relieves premenstrual mood changes. Obstet Gynecol. 1991; 78:177-181.
• Fairbanks VF. Iron in medicine and nutrition. In: Shils ME, Olson JA, Shike M, Ross AC, eds. Modern Nutrition in Health and Disease. Baltimore, MD: Williams and Wilkins; 1999:193-221.
• Fang J, Madhavan S, Alderman MH. Dietary potassium intake and stroke mortality. Stroke. 2000; 31:1532-1537.
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• Futoryan T, Gilchrest BA. Retinoids and the skin. Nutr Rev. 1994; 52:299-310.
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• Harris ED. Cellular copper transport and metabolism. Annu Rev Nutr. 2000; 20:291-310.
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Isotonix® Activated B-Complex

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Isotonix® Calcium Plus

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